
65 nightsFrom Miami, Florida34 ports of call
South American Adventure - Miami to Miami
Oceania Cruises · Sirena
Overview
A 65-night voyage aboard Sirena, departing Miami, Florida on 5 Jan 2028 and returning to the same port, calling at 34 destinations along the way.
Miami, FloridaGeorge Town, Cayman IslandsOcho RiosSanta MartaCartagena, ColombiaColon, PanamaPanama CanalMantaSalaverry (Trujillo)Lima, PeruPisco, PeruAricaAntofagasta, ChileValparaisoPuerto MonttCastro, Chiloe IslandPuerto Chacabuco, ChilePunta Arenas, ChileUshuaia, ArgentinaPort StanleyPuerto MadrynBuenos AiresPunta del EsteRio de JaneiroMaceioSantaremBoca De ValeiraManausParintinsAlter Do Chao, BrazilBridgetown, BarbadosPoint-a-PitreTortolaMiami, Florida
Cabin prices
Live prices per person based on two sharing. Select a grade to see its fare options.
Loading live cabin prices…
Itinerary
65 nights · 66 ports of call- 1
Day 1 ·MiamiEmbark
5 Jan 2028Depart 17:00People-watchers will enjoy South Beach's Ocean Drive, while architecture buffs will love the Art Deco District. If you're looking for something a bit different, there are world-class museums and shopping venues too. In Miami, there really is something for everyone. - 2
Day 2 ·At Sea
6 Jan 2028 - 3
Day 3 ·George Town, Grand Cayman
7 Jan 2028Arrive 11:00Depart 19:00Swim and snorkel with shy and gentle stingrays, see the underwater world from a semi-submersible sub, send a postcard from "Hell," visit a turtle farm where green sea turtles are raised, or just relax on miles and miles of exquisite white sand beach. - 4
Day 4 ·Ocho Rios
8 Jan 2028Arrive 11:00Depart 20:00Believed to have been the first place Christopher Columbus set foot in Jamaica, Columbus Park is just outside the city limits and features maritime artifacts and several Spanish colonial buildings. Swim with dolphins in Dolphin Cove, relax on the beaches of the many resorts in the area or visit Dunn’s River Falls, one of Jamaica’s most famous attractions. - 5
Day 5 ·At Sea
9 Jan 2028 - 6
Day 6 ·Santa Marta
10 Jan 2028Arrive 07:00Depart 18:00From the mangroves of Ciénaga Grande to the beaches of Tayrona National Park, Santa Marta offers a multitude of thrilling adventures. The oldest city in Colombia, it abounds with Spanish colonial charm, including one of the first basilicas built in Latin America, the Cathedral of Santa Marta. To learn of ancient history, explore the Ciudad Perdida, or “Lost City,” believed to have been founded 650 years before Machu Picchu. - 7
Day 7 ·Cartagena, Colombia
11 Jan 2028Arrive 07:00Depart 19:00Take a scenic drive through the residential area of Manga and admire the beautiful mansions. Explore the Castillo San Felipe de Barajas, a fort that was once the most important military structure built in Latin America. Enjoy a boat ride to the Islas del Rosario and continue to the island of San Martín de Pajarales to visit the aquarium. Board a beautiful Spanish galleon, a replica of a 17th century sailing ship, for a cruise of the inner bay of Cartagena. - 8
Day 8 ·Colon
12 Jan 2028Arrive 08:00See how the Panama Canal operates with a visit to the locks. Or ride a train across the isthmus. Discover Panama's lush rainforest and its resident wildlife as you walk a forest trail or take a boat ride down a quiet river. - 9
Day 9 ·Panama Canal
13 Jan 2028The Panama Canal is an artificial 82 km waterway in Panama that connects the Atlantic Ocean with the Pacific Ocean. The canal cuts across the Isthmus of Panama and is a conduit for maritime trade. - 10
Day 10 ·At Sea
14 Jan 2028 - 11
Day 11 ·Manta, Ecuador
15 Jan 2028Arrive 07:00Depart 17:00As a gateway to Equador, the small port city of Manta is a short drive from Montecristi, where the world's best Panama hats are produced and where they originated. Catch a flight to the capital city of Quito, a wonderfully preserved colonial-era city perched 9,200 feet above sea level. Beautiful lakes, volcanoes and high mountains around the town of Otavalo are spectacular. - 12
Day 12 ·At Sea
16 Jan 2028 - 13
Day 13 ·Salaverry
17 Jan 2028Arrive 07:00Depart 16:00Founded by the Spanish conquistador Pizarro, Salaverry has numerous archaeological excavations and is a jumping-off spot for a visit to Machu Picchu. The "Lost City of the Incas" is one of South America's most intriguing archaeological sites. Machu Picchu is perched 7,875 feet above sea level and has a 1,800-foot vertical drop face. What remains are extraordinary stone buildings built by the Incas for use as temples, sanctuaries and homes. This UNESCO World Heritage Site was originally built in 1460. - 14
Day 14 ·Lima/Machu Picchu (Callao), Peru
18 Jan 2028Arrive 11:00Explore Lima’s wonderful museums and visit the famed Cathedral of Lima and the Archbishop’s Palace on the city’s majestic main square. Take a flight to Machu Picchu, known as the “Lost City of the Incas” and South America’s most intriguing archaeological site. Built in the 15th century by the Incas and perched 7,875 feet above sea level, this extraordinary UNESCO World Heritage Site features stone buildings once used as temples, sanctuaries, homes and water fountains. Also enchanting is the colonial city of Cuzco with its majestic Plaza de Armas and the ancient Incan fortress of Sacsayhuaman. - 15
Day 15 ·Lima/Machu Picchu (Callao), Peru
19 Jan 2028Arrive 07:00Depart 17:00Explore Lima’s wonderful museums and visit the famed Cathedral of Lima and the Archbishop’s Palace on the city’s majestic main square. Take a flight to Machu Picchu, known as the “Lost City of the Incas” and South America’s most intriguing archaeological site. Built in the 15th century by the Incas and perched 7,875 feet above sea level, this extraordinary UNESCO World Heritage Site features stone buildings once used as temples, sanctuaries, homes and water fountains. Also enchanting is the colonial city of Cuzco with its majestic Plaza de Armas and the ancient Incan fortress of Sacsayhuaman. - 16
Day 16 ·Pisco/Nazca Lines
20 Jan 2028Arrive 08:00Depart 17:00Wander through this entrancing fishing village at the edge of the desert; it rains only once every 25 years. Marvel at the Nazca Lines, geoglyphs carved into the desert floor by pre-Incan societies, over 300 figural drawings that remain virtually undamaged through the centuries. - 17
Day 17 ·At Sea
21 Jan 2028 - 18
Day 18 ·Arica
22 Jan 2028Depart 17:00Arica (/əˈriːkə/ ə-REE-kə; Spanish: [aˈɾika]) is a commune and a port city with a population of 222,619 in the Arica Province of northern Chile's Arica y Parinacota Region. It is Chile's northernmost city, being located only 18 km - 19
Day 19 ·At Sea
23 Jan 2028 - 20
Day 20 ·Antofagasta
24 Jan 2028Arrive 07:00Depart 17:00The Antofagasta Region is one of Chile's sixteen first-order administrative divisions. The second-largest region of Chile, it comprises three provinces, Antofagasta, El Loa and Tocopilla. It is bordered to the north by Tarapacá, by Atacama to the south, and to the east by Bolivia and Argentina. - 21
Day 21 ·At Sea
25 Jan 2028 - 22
Day 22 ·Valparaiso
26 Jan 2028Arrive 07:00Depart 16:00Enjoy the charming chaos and color of the hillside old quarter, or visit lovely nearby Viña del Mar and its famed floral clock. Or head inland to Chile's scenic Central Valley, the country's breadbasket, and on to the Andes with their world-class vineyards and ski resorts. Many will want to spend the day in metropolitan Santiago, considered the safest city in Latin America. - 23
Day 23 ·At Sea
27 Jan 2028 - 24
Day 24 ·Puerto Montt
28 Jan 2028Arrive 08:00Depart 18:00Enjoy the Bavarian ambiance of the Lake District as you visit the edge of the Patagonian wilderness, seeing pristine wood forests, vast lakes, soaring waterfalls, snow-capped peaks and spectacular vistas. - 25
Day 25 ·Castro
29 Jan 2028Arrive 07:00Depart 16:00 - 26
Day 26 ·Puerto Chacabuco
30 Jan 2028Arrive 09:00Depart 18:00Experience a bit of rugged Patagonia with a drive into the Andes Mountains through a stunning valley to the Rio Simpson National Reserve and the town of Coyhaique. Or visit the magnificent private Aikén del Sur Park with its many waterfalls, wetlands, forests and mosses. - 27
Day 27 ·Cruising the Chilean Fjords
31 Jan 2028Sail through some of the world's narrowest and most scenic waterways. Near the serrated southern tip of Chile, the Southern Andes plunge into icy waters, leaving a region so wild and remote that it has been virtually untouched since the beginning of time. It is here in Chile's fjords that ancient glaciers sliced their way between the mountains, leaving isolated islands and hidden coves upon their retreat. - 28
Day 28 ·Cruising the Chilean Fjords
1 Feb 2028Sail through some of the world's narrowest and most scenic waterways. Near the serrated southern tip of Chile, the Southern Andes plunge into icy waters, leaving a region so wild and remote that it has been virtually untouched since the beginning of time. It is here in Chile's fjords that ancient glaciers sliced their way between the mountains, leaving isolated islands and hidden coves upon their retreat. - 29
Day 29 ·Punta Arenas, Chile
2 Feb 2028Arrive 07:00Depart 17:00Explore the town and its history and enjoy stunning views over the Strait of Magellan to fabled Tierra del Fuego. Discover the scenic Patagonian countryside and visit a local sheep farm. The highlight is the Magellanic penguin rookery at Otway Sound. Or fly to Chile's magnificent Torres Del Paine National Park. - 30
Day 30 ·Ushuaia
3 Feb 2028Arrive 11:00Depart 20:00Witness the spectacular beauty of Tierra del Fuego’s lakes, lush forests, soaring mountains and flora and fauna by train, via all-terrain vehicle or on horseback. Enjoy the expansive views from Garibaldi Pass and watch for sea lions and albatross along the Beagle Channel. - 31
Day 31 ·At Sea
4 Feb 2028 - 32
Day 32 ·At Sea
5 Feb 2028 - 33
Day 33 ·Cruising the Antarctic Peninsula
6 Feb 2028 - 34
Day 34 ·Cruising the Antarctic Peninsula
7 Feb 2028 - 35
Day 35 ·At Sea
8 Feb 2028 - 36
Day 36 ·Port Stanley, Falkland Islands
9 Feb 2028Arrive 07:00Depart 16:00Discover this quaint town, its cathedral, authentic English pubs, neat gardens, war memorials and fascinating landscape. Set off for an adventure on this South Atlantic island and visit a penguin colony and watch for albatross and skuas or go to a sprawling sheep farm. - 37
Day 37 ·At Sea
10 Feb 2028 - 38
Day 38 ·Puerto Madryn
11 Feb 2028Arrive 08:00Depart 17:00Explore this wildlife paradise and its surrounding quaint towns. Visit an exuberant sea lion colony, watch for nesting cormorants and magnificent elephant seals, and observe sheep-shearing on an estancia. Or experience a walk through a colony of Magellanic penguins and myriad species of native seabirds. - 39
Day 39 ·At Sea
12 Feb 2028 - 40
Day 40 ·At Sea
13 Feb 2028 - 41
Day 41 ·Buenos Aires, Argentina
14 Feb 2028Arrive 08:00Depart 17:00Discover this elegant city and its beautiful surroundings with a tranquil cruise through the Tigre Delta past islands, mansions and English gardens. Visit the pampas and watch gauchos display their extraordinary horsemanship, or enjoy a fabulous tango show in its birthplace. - 42
Day 42 ·Punta Del Este
15 Feb 2028Arrive 08:00Depart 18:00Spend the day enjoying this beautiful, chic beach resort, its marinas and interesting shops. See amazing works by Dali, Chagall and Miro at the Ralli Museum. Or venture into the equally stunning countryside and visit a cattle station. Shopping: - 43
Day 43 ·At Sea
16 Feb 2028 - 44
Day 44 ·At Sea
17 Feb 2028 - 45
Day 45 ·Rio De Janeiro
18 Feb 2028Arrive 07:00Depart 17:00Enjoy a scenic cable car ride to the top of Sugarloaf Mountain for its renowned view. Ride the cog railway through dense forest to Corcovado. Visit the lush botanical gardens, see famed Ipanema and Copacabana beaches and take in a thrilling samba show. - 46
Day 46 ·At Sea
19 Feb 2028 - 47
Day 47 ·At Sea
20 Feb 2028 - 48
Day 48 ·Maceio, Brazil
21 Feb 2028Arrive 07:00Depart 17:00Wrapped around a sparkling lagoon that links up with the sea, Maceió is a modern tourist destination with a reverence for its Portuguese colonial past. Spot architectural jewels including the stunning blue-and-white-tiled Bom Jesus dos Martírios church and take in a sweeping panorama of the city from the São Gonçalo Belvedere. For an authentic keepsake, select among a rainbow of rendas, traditional lacework evocative of fish netting that has been dyed in tropical colors. It’s no surprise that in Maceió water activities reign supreme, including a catamaran cruise over the Mundaú Lagoon to a secluded beach for the ultimate respite under the sun. - 49
Day 49 ·At Sea
22 Feb 2028 - 50
Day 50 ·At Sea
23 Feb 2028 - 51
Day 51 ·At Sea
24 Feb 2028 - 52
Day 52 ·Cruising the Amazon River
25 Feb 2028Many travelers begin their Amazon experience in Manaus, Brazil. Others begin at the "end of the line", in Belém or Macapa, where the Amazon flows into the Atlantic Ocean. - 53
Day 53 ·Santarem
26 Feb 2028Arrive 08:00Depart 17:00See the bustling waterfront, the cathedral, the museum and the famed “Meeting of the Waters” at the confluence of the Tapajos and Amazon rivers. Or see the rivers converge from a boat on the way to Maica Lake, while looking for rare Amazon pink dolphins. Travel into the nearby countryside and take a walk along a fascinating Amazon jungle trail. - 54
Day 54 ·Boca da Valeria (Amazon River), Brazil
27 Feb 2028Arrive 07:00Depart 14:00Go ashore and wander on your own through this tiny settlement at the mouth of the Valeria River. Listen to the screeching of parrots and watch the riots of color they display as they take to the air. Observe Amazonian life up close. - 55
Day 55 ·Manaus
28 Feb 2028Arrive 09:00Depart 17:00Visit the famed Manaus Opera House. See the old mansions and the Indian Museum, featuring artifacts that chronicle the heritage of the region’s tribes. Journey into the jungle and trek along a rainforest trail. Take a riverboat to the “Meeting of the Waters,” where the dark, clear Rio Negro and the muddy, yellow Rio Solimões join to form the mighty Amazon. - 56
Day 56 ·Parintins
29 Feb 2028Arrive 10:00Depart 19:00Visit this isolated island town, steeped in Indian culture, in the middle of the Amazon River. Its stadium has become the focus of the Boi Bumba Festival, an annual event similar to Carnival. Witness an exclusive performance of this Amazonian folklore story. - 57
Day 57 ·Alter Do Chao
1 Mar 2028Arrive 07:00Depart 18:00Home to Ilha do Amor, one of the most photographed white sand islands in the entire world, Alter do Chão is a charming riverside village. Explore Lago Verde, a grand lagoon that can viewed from rented canoes, or take a boat tour along the Rio Tapajós or the Amazon. You’ll see a number of bird species and might even spot a crocodile or a sloth. Try Serra Pelada if you seek the perfect place for a short but breathtaking hike. - 58
Day 58 ·At Sea
2 Mar 2028 - 59
Day 59 ·At Sea
3 Mar 2028 - 60
Day 60 ·At Sea
4 Mar 2028 - 61
Day 61 ·Bridgetown, Barbados
5 Mar 2028Arrive 09:00Depart 18:00Discover the many beautiful aspects of this island, from its rugged Atlantic coastline to its beautiful Great Houses, cane fields, exquisite gardens and glorious beaches. See the island's spectacular underwater treasures on your own snorkeling expedition. - 62
Day 62 ·Pointe-à-Pitre
6 Mar 2028Arrive 09:00Depart 17:00Sometimes referred to as “Butterfly Island” because of its shape, Guadeloupe is an overseas region of France. Whether visiting the spectacular waterfalls in the jungle of Basse-Terre, taking a scenic hike to the top of La Grande Soufrière volcano or sampling local rum on a distillery tour, you will find a diverse array of activities to enjoy. - 63
Day 63 ·Tortola
7 Mar 2028Arrive 10:00Depart 18:00Spend a glorious day swimming at famed Cane Garden Bay Beach, hiking in the rainforest or enjoying a scenic drive around this lush island. Swim with dolphins, go sea kayaking, or head over to Virgin Gorda and climb down to the famous Baths for a day of swimming and exploring this natural phenomenon. - 64
Day 64 ·At Sea
8 Mar 2028 - 65
Day 65 ·At Sea
9 Mar 2028 - 66
Day 66 ·MiamiDisembark
10 Mar 2028Arrive 08:00People-watchers will enjoy South Beach's Ocean Drive, while architecture buffs will love the Art Deco District. If you're looking for something a bit different, there are world-class museums and shopping venues too. In Miami, there really is something for everyone.
Your ship: Sirena

Explore Sirena's cabins, dining and onboard facilities.
