
10 nightsFrom Istanbul11 ports of call
Istanbul to Rome
Oceania Cruises · Sirena
Overview
A 10-night voyage aboard Sirena, departing Istanbul on 9 Jul 2027 and arriving in Civitavecchia, Rome, calling at 11 destinations along the way.
IstanbulMitilini (Lesvos)Kavala, GreeceThessalonikiMykonosSantoriniCreteOlympia (Katakolon), GreeceTaorminaAmalfi, ItalyCivitavecchia, Rome
Cabin prices
Live prices per person based on two sharing. Select a grade to see its fare options.
Loading live cabin prices…
Itinerary
10 nights · 11 ports of call- 1
Day 1 ·Istanbul, TurkeyEmbark
9 Jul 2027Depart 17:00Indulge your eyes and senses in this magnificent city astride two continents. Visit beautiful Topkapi Palace, the awesome Hagia Sophia and the impressive Blue Mosque. Cruise the Bosphorus to see the city and its surroundings from another perspective. Visit one of the many museums or stroll through the spice market and the famous Grand Bazaar. - 2
Day 2 ·Mitilini (Lesbos)
10 Jul 2027Arrive 10:00Depart 19:00Explore this bustling city's ancient roots, and visit the huge castle perched on the hill - the beautiful Greek theater that the Romans repaired and then copied back in Rome! See the impressive Cathedral and the Church of St. Nicholas, converted from a mosque. Enjoy the Archaeological Museum or one of the fine art museums with collections of important works. Venture into the old quarter near the waterfront to enjoy the old Turkish mansions or into the countryside and discover quaint villages where time has stopped. - 4
Day 4 ·Kavala
11 Jul 2027Arrive 12:00Depart 20:00Built on a promontory on the site of ancient Neapolis, Kavala offers fine beaches and numerous historic sites. A Byzantine castle lords over Kavala, and its 16th century aqueduct is still intact. The ruins of nearby Philippi include a Roman forum and a 5th century cathedral. - 4
Day 4 ·Thessaloniki
12 Jul 2027Depart 19:00With a history spanning more than two millennia, Thessaloniki reigned alongside Constantinople as a capital of the Byzantine Empire. So numerous are the outstanding Paleochristian and Byzantine monuments that as a group they have been designated a UNESCO World Heritage Site. Don’t miss the ornate church and sacred crypt of St. Demetrius, the city’s martyred patron saint, or the palace complex of Galerius and the mosaics in the Rotunda. The Archaeological Museum holds even more ancient treasures. - 5
Day 5 ·Mykonos
13 Jul 2027Arrive 09:00Depart 21:00Enjoy wandering through the narrow, winding streets of this delightful seaside village with its whitewashed houses, flowers and brightly painted shutters and doors. Stand beneath the windmills on the hill. Visit the archaeological museum and an old bakery still using a 15th century wood-burning stove. - 6
Day 6 ·Santorini, Greece
14 Jul 2027Arrive 09:00Depart 18:00Visit the beautiful whitewashed hilltop towns of Oia and Fira and their breathtaking views of the caldera below. See the stunning artifacts in Fira's museum, including recent finds from the excavation of Akrotiri, thought by many to be the legendary city of Atlantis, or visit a winery. Stroll through the winding streets with fantastic views around every corner. - 7
Day 7 ·Aghios Nikolaos (Crete)
15 Jul 2027Arrive 07:00Depart 16:00Agios Nikolaos, Hagios Nikolaos or Aghios Nikolaos (Greek: Άγιος Νικόλαος [ˈaʝoz niˈkolaos]) is a coastal town on the Greek island of Crete, lying east of the island's capital Heraklion, north of the town of Ierapetra and west of the town of Sitia. - 8
Day 8 ·Katakolon, Greece
16 Jul 2027Arrive 10:00Depart 18:00Visit ancient Olympia where the Olympic Games began in 776 B.C. and stroll around this deserted sanctuary, admiring the temples, altars and treasuries, and stand on the ground where ancient athletes practiced before competing. Or enjoy a pleasant drive through the countryside past quaint villages to a local vineyard and sample the wines, local cheeses and other foods. - 9
Day 9 ·Taormina (Sicily)
17 Jul 2027Arrive 11:00Depart 20:00Enjoy magnificent panoramic views on the way up to the town, where you can stroll down medieval lanes past stunning palaces. See the famed Greek theater and its fantastic view of Mount Etna. Or take a trip to the volcano itself and get a first-hand look at cones, craters and lava streams from previous eruptions and a fantastic view over the Gulf of Catania. Venture into the countryside and its lovely hill towns, one with a Norman castle built of black lava, and visit beautiful old Catania. - 10
Day 10 ·Amalfi, Positano
18 Jul 2027Arrive 08:00Depart 18:00Visit enchanting Amalfi to admire the 12th century Capuchin monastery and see the beautiful 11th century cathedral and cloister. Then discover chic Positano with its relaxed, sophisticated air and white Moorish-style houses clinging to steep slopes around a sparkling bay filled with colorful fishing boats. - 11
Day 11 ·Rome, (Civitavecchia)Disembark
19 Jul 2027Arrive 07:00Travel to Rome and revel in the magnificent monuments, from the ancient Roman Forum and Coliseum to the splendor of St. Peter's Basilica with Michelangelo's Pietà and his breathtaking frescoes in the Sistine Chapel. Or enjoy a drive through the lush farmlands of the Roman countryside to lovely medieval Castelgandolfo.
Your ship: Sirena

Explore Sirena's cabins, dining and onboard facilities.
