
7 nightsFrom Civitavecchia, Rome7 ports of call
Rome to Istanbul
Oceania Cruises · Sirena
Overview
A 7-night voyage aboard Sirena, departing Civitavecchia, Rome on 5 Nov 2026 and arriving in Istanbul, calling at 7 destinations along the way.
Civitavecchia, RomeNaplesMessina, ItalyMaltaAthens (Piraeus), GreeceMitilini (Lesvos)Istanbul
Cabin prices
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Itinerary
7 nights · 8 ports of call- 1
Day 1 ·Rome, (Civitavecchia)Embark
5 Nov 2026Depart 17:00Travel to Rome and revel in the magnificent monuments, from the ancient Roman Forum and Coliseum to the splendor of St. Peter's Basilica with Michelangelo's Pietà and his breathtaking frescoes in the Sistine Chapel. Or enjoy a drive through the lush farmlands of the Roman countryside to lovely medieval Castelgandolfo. - 2
Day 2 ·Naples/Pompeii
6 Nov 2026Arrive 07:00Depart 18:00Spend a day exploring the fabulous ruins of ancient Pompeii or Herculaneum with their stunning temples, frescoes and mosaics. Explore fascinating Naples and its famed museums, visit charming Sorrento or take a boat trip to the beautiful Isle of Capri. - 3
Day 3 ·Messina
7 Nov 2026Arrive 07:00Depart 19:00Visit beautiful Taormina and marvel at its famous Greek theater and the stunning view of Mount Etna. Explore lovely medieval Messina with its historic churches and the cathedral where it is rumored Richard the Lionheart worshipped in 1190. Or discover ancient Tyndaris, founded in 396 B.C., with its fine mosaics, Roman baths and impressive theater overlooking the sea. - 4
Day 4 ·Valletta
8 Nov 2026Arrive 07:00Depart 19:00Discover the myriad of cultural layers of Malta, from its amazing prehistoric temples at Tarxien to beautiful walled medieval Mdina, nearby Rabat, and Marsaxlokk, a colorful fishing village. Admire the stunning scenery and wander through imposing churches and down the streets of fortified towns where the Knights of St. John once held sway. - 5
Day 5 ·At Sea
9 Nov 2026 - 6
Day 6 ·Athens (Piraeus)
10 Nov 2026Arrive 07:00Depart 17:00Climb up the magnificent Acropolis and stand in awe of the Parthenon, the beautiful temples and the view over Athens stretched out before you. See city highlights including the new and old Olympic stadiums. Journey to Cape Sounion and the temple of Poseidon overlooking the sea, or visit ancient Corinth and the narrow Corinth Canal cut through miles of solid rock. - 7
Day 7 ·Mitilini (Lesbos)
11 Nov 2026Arrive 07:00Depart 14:00Explore this bustling city's ancient roots, and visit the huge castle perched on the hill - the beautiful Greek theater that the Romans repaired and then copied back in Rome! See the impressive Cathedral and the Church of St. Nicholas, converted from a mosque. Enjoy the Archaeological Museum or one of the fine art museums with collections of important works. Venture into the old quarter near the waterfront to enjoy the old Turkish mansions or into the countryside and discover quaint villages where time has stopped. - 8
Day 8 ·Istanbul, TurkeyDisembark
12 Nov 2026Arrive 08:00Indulge your eyes and senses in this magnificent city astride two continents. Visit beautiful Topkapi Palace, the awesome Hagia Sophia and the impressive Blue Mosque. Cruise the Bosphorus to see the city and its surroundings from another perspective. Visit one of the many museums or stroll through the spice market and the famous Grand Bazaar.
Your ship: Sirena

Explore Sirena's cabins, dining and onboard facilities.
